Identification and adjustment of experimental occlusal interference using functional magnetic resonance imaging
Identifieur interne : 000B82 ( Pmc/Curation ); précédent : 000B81; suivant : 000B83Identification and adjustment of experimental occlusal interference using functional magnetic resonance imaging
Auteurs : Masafumi Oda [Japon] ; Kenichi Yoshino [Japon] ; Tatsurou Tanaka [Japon] ; Shunji Shiiba [Japon] ; Eri Makihara [Japon] ; Ikuya Miyamoto [Japon] ; Shinnosuke Nogami [Japon] ; Shinji Kito [Japon] ; Nao Wakasugi-Sato [Japon] ; Shinobu Matsumoto-Takeda [Japon] ; Shun Nishimura [Japon] ; Keita Murakami [Japon] ; Masahiro Koga [Japon] ; Shigenori Kawagishi [Japon] ; Izumi Yoshioka [Japon] ; Shin-Ichi Masumi [Japon] ; Mitsutaka Kimura [Japon] ; Yasuhiro Morimoto [Japon]Source :
- BMC Oral Health [ 1472-6831 ] ; 2014.
Abstract
The purpose of this study was to use functional magnetic resonance imaging (fMRI) to quantify changes in brain activity during experimental occlusal interference.
Fourteen healthy volunteers performed a rhythmical tapping occlusion task with experimental occlusal interference of the right molar tooth at 0 mm (no occlusion), 0.5 mm, and 0.75 mm. The blood-oxygen-level dependent (BOLD) signal was quantified using statistical parametric mapping and compared between rest periods and task periods.
In tapping tasks with experimental occlusal interference of 0.75 mm or 0.5 mm, there was clear activation of the contralateral teeth-related primary sensory cortex and Brodmann’s area 46. At 0 and 30 minutes after removal of the experimental occlusal interference, the activation clearly appeared in the bilateral teeth-related primary sensory cortices and Brodmann’s area 46. At 60 minutes after the removal of the experimental occlusal interference, the activation of Brodmann’s area 46 had disappeared, and only the bilateral teeth-related primary sensory cortices were active.
The present results suggest that adjustments for experimental occlusal interference can be objectively evaluated using fMRI. We expect that this method of evaluating adjustments in occlusal interference, combined with fMRI and the tapping task, could be applied clinically in the future.
Url:
DOI: 10.1186/1472-6831-14-124
PubMed: 25304016
PubMed Central: 4200220
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Kitakyushu</wicri:regionArea></affiliation></author><author><name sortKey="Nishimura, Shun" sort="Nishimura, Shun" uniqKey="Nishimura S" first="Shun" last="Nishimura">Shun Nishimura</name><affiliation wicri:level="1"><nlm:aff id="Aff1">Division of Oral and Maxillofacial Radiology, Kyushu Dental University, Kitakyushu, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Division of Oral and Maxillofacial Radiology, Kyushu Dental University, Kitakyushu</wicri:regionArea></affiliation></author><author><name sortKey="Murakami, Keita" sort="Murakami, Keita" uniqKey="Murakami K" first="Keita" last="Murakami">Keita Murakami</name><affiliation wicri:level="1"><nlm:aff id="Aff1">Division of Oral and Maxillofacial Radiology, Kyushu Dental University, Kitakyushu, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Division of Oral and Maxillofacial Radiology, Kyushu Dental University, Kitakyushu</wicri:regionArea></affiliation></author><author><name 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wicri:level="1"><nlm:aff id="Aff1">Division of Oral and Maxillofacial Radiology, Kyushu Dental University, Kitakyushu, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Division of Oral and Maxillofacial Radiology, Kyushu Dental University, Kitakyushu</wicri:regionArea></affiliation></author><author><name sortKey="Yoshino, Kenichi" sort="Yoshino, Kenichi" uniqKey="Yoshino K" first="Kenichi" last="Yoshino">Kenichi Yoshino</name><affiliation wicri:level="1"><nlm:aff id="Aff2">Department of Oral Health Management, School of Oral Health Sciences, Kyushu Dental University, Kitakyushu, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Oral Health Management, School of Oral Health Sciences, Kyushu Dental University, Kitakyushu</wicri:regionArea></affiliation></author><author><name sortKey="Tanaka, Tatsurou" sort="Tanaka, Tatsurou" uniqKey="Tanaka T" first="Tatsurou" last="Tanaka">Tatsurou Tanaka</name><affiliation wicri:level="1"><nlm:aff id="Aff1">Division of Oral and Maxillofacial Radiology, Kyushu Dental University, Kitakyushu, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Division of Oral and Maxillofacial Radiology, Kyushu Dental University, Kitakyushu</wicri:regionArea></affiliation></author><author><name sortKey="Shiiba, Shunji" sort="Shiiba, Shunji" uniqKey="Shiiba S" first="Shunji" last="Shiiba">Shunji Shiiba</name><affiliation wicri:level="1"><nlm:aff id="Aff3">Division of Dental Anesthesiology, Kyushu Dental University, Kitakyushu, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Division of Dental Anesthesiology, Kyushu Dental University, Kitakyushu</wicri:regionArea></affiliation></author><author><name sortKey="Makihara, Eri" sort="Makihara, Eri" uniqKey="Makihara E" first="Eri" last="Makihara">Eri Makihara</name><affiliation wicri:level="1"><nlm:aff id="Aff4">Division of Occlusion and Maxillofacial Reconstruction, Kyushu Dental University, Kitakyushu, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Division of Occlusion and Maxillofacial Reconstruction, Kyushu Dental University, Kitakyushu</wicri:regionArea></affiliation></author><author><name sortKey="Miyamoto, Ikuya" sort="Miyamoto, Ikuya" uniqKey="Miyamoto I" first="Ikuya" last="Miyamoto">Ikuya Miyamoto</name><affiliation wicri:level="1"><nlm:aff id="Aff5">Division of Oral Medicine, Kyushu Dental University, Kitakyushu, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Division of Oral Medicine, Kyushu Dental University, Kitakyushu</wicri:regionArea></affiliation></author><author><name sortKey="Nogami, Shinnosuke" sort="Nogami, Shinnosuke" uniqKey="Nogami S" first="Shinnosuke" last="Nogami">Shinnosuke Nogami</name><affiliation wicri:level="1"><nlm:aff id="Aff6">Division of Oral and Maxillofacial Surgery, Tohoku University Graduate School of Dentistry, Sendai, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Division of Oral and Maxillofacial Surgery, Tohoku University Graduate School of Dentistry, Sendai</wicri:regionArea></affiliation></author><author><name sortKey="Kito, Shinji" sort="Kito, Shinji" uniqKey="Kito S" first="Shinji" last="Kito">Shinji Kito</name><affiliation wicri:level="1"><nlm:aff id="Aff1">Division of Oral and Maxillofacial Radiology, Kyushu Dental University, Kitakyushu, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Division of Oral and Maxillofacial Radiology, Kyushu Dental University, Kitakyushu</wicri:regionArea></affiliation></author><author><name sortKey="Wakasugi Sato, Nao" sort="Wakasugi Sato, Nao" uniqKey="Wakasugi Sato N" first="Nao" last="Wakasugi-Sato">Nao Wakasugi-Sato</name><affiliation wicri:level="1"><nlm:aff id="Aff1">Division of Oral and Maxillofacial Radiology, Kyushu Dental University, Kitakyushu, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Division of Oral and Maxillofacial Radiology, Kyushu Dental University, Kitakyushu</wicri:regionArea></affiliation></author><author><name sortKey="Matsumoto Takeda, Shinobu" sort="Matsumoto Takeda, Shinobu" uniqKey="Matsumoto Takeda S" first="Shinobu" last="Matsumoto-Takeda">Shinobu Matsumoto-Takeda</name><affiliation wicri:level="1"><nlm:aff id="Aff1">Division of Oral and Maxillofacial Radiology, Kyushu Dental University, Kitakyushu, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Division of Oral and Maxillofacial Radiology, Kyushu Dental University, Kitakyushu</wicri:regionArea></affiliation></author><author><name sortKey="Nishimura, Shun" sort="Nishimura, Shun" uniqKey="Nishimura S" first="Shun" last="Nishimura">Shun Nishimura</name><affiliation wicri:level="1"><nlm:aff id="Aff1">Division of Oral and Maxillofacial Radiology, Kyushu Dental University, Kitakyushu, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Division of Oral and Maxillofacial Radiology, Kyushu Dental University, Kitakyushu</wicri:regionArea></affiliation></author><author><name sortKey="Murakami, Keita" sort="Murakami, Keita" uniqKey="Murakami K" first="Keita" last="Murakami">Keita Murakami</name><affiliation wicri:level="1"><nlm:aff id="Aff1">Division of Oral and Maxillofacial Radiology, Kyushu Dental University, Kitakyushu, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Division of Oral and Maxillofacial Radiology, Kyushu Dental University, Kitakyushu</wicri:regionArea></affiliation></author><author><name sortKey="Koga, Masahiro" sort="Koga, Masahiro" uniqKey="Koga M" first="Masahiro" last="Koga">Masahiro Koga</name><affiliation wicri:level="1"><nlm:aff id="Aff1">Division of Oral and Maxillofacial Radiology, Kyushu Dental University, Kitakyushu, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Division of Oral and Maxillofacial Radiology, Kyushu Dental University, Kitakyushu</wicri:regionArea></affiliation></author><author><name sortKey="Kawagishi, Shigenori" sort="Kawagishi, Shigenori" uniqKey="Kawagishi S" first="Shigenori" last="Kawagishi">Shigenori Kawagishi</name><affiliation wicri:level="1"><nlm:aff id="Aff7">Division of Multidisciplinary Studies, Kyushu Dental University, Kitakyushu, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Division of Multidisciplinary Studies, Kyushu Dental University, Kitakyushu</wicri:regionArea></affiliation></author><author><name sortKey="Yoshioka, Izumi" sort="Yoshioka, Izumi" uniqKey="Yoshioka I" first="Izumi" last="Yoshioka">Izumi Yoshioka</name><affiliation wicri:level="1"><nlm:aff id="Aff5">Division of Oral Medicine, Kyushu Dental University, Kitakyushu, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Division of Oral Medicine, Kyushu Dental University, Kitakyushu</wicri:regionArea></affiliation></author><author><name sortKey="Masumi, Shin Ichi" sort="Masumi, Shin Ichi" uniqKey="Masumi S" first="Shin-Ichi" last="Masumi">Shin-Ichi Masumi</name><affiliation wicri:level="1"><nlm:aff id="Aff4">Division of Occlusion and Maxillofacial Reconstruction, Kyushu Dental University, Kitakyushu, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Division of Occlusion and Maxillofacial Reconstruction, Kyushu Dental University, Kitakyushu</wicri:regionArea></affiliation></author><author><name sortKey="Kimura, Mitsutaka" sort="Kimura, Mitsutaka" uniqKey="Kimura M" first="Mitsutaka" last="Kimura">Mitsutaka Kimura</name><affiliation wicri:level="1"><nlm:aff id="Aff8">Kyushu Dental University, Kitakyushu, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Kyushu Dental University, Kitakyushu</wicri:regionArea></affiliation></author><author><name sortKey="Morimoto, Yasuhiro" sort="Morimoto, Yasuhiro" uniqKey="Morimoto Y" first="Yasuhiro" last="Morimoto">Yasuhiro Morimoto</name><affiliation wicri:level="1"><nlm:aff id="Aff1">Division of Oral and Maxillofacial Radiology, Kyushu Dental University, Kitakyushu, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Division of Oral and Maxillofacial Radiology, Kyushu Dental University, Kitakyushu</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="Aff9">Center for Oral Biological Research, Kyushu Dental University, Kitakyushu, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Center for Oral Biological Research, Kyushu Dental University, Kitakyushu</wicri:regionArea></affiliation></author></analytic><series><title level="j">BMC Oral Health</title><idno type="eISSN">1472-6831</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Background</title><p>The purpose of this study was to use functional magnetic resonance imaging (fMRI) to quantify changes in brain activity during experimental occlusal interference.</p></sec><sec><title>Methods</title><p>Fourteen healthy volunteers performed a rhythmical tapping occlusion task with experimental occlusal interference of the right molar tooth at 0 mm (no occlusion), 0.5 mm, and 0.75 mm. The blood-oxygen-level dependent (BOLD) signal was quantified using statistical parametric mapping and compared between rest periods and task periods.</p></sec><sec><title>Results</title><p>In tapping tasks with experimental occlusal interference of 0.75 mm or 0.5 mm, there was clear activation of the contralateral teeth-related primary sensory cortex and Brodmann’s area 46. At 0 and 30 minutes after removal of the experimental occlusal interference, the activation clearly appeared in the bilateral teeth-related primary sensory cortices and Brodmann’s area 46. At 60 minutes after the removal of the experimental occlusal interference, the activation of Brodmann’s area 46 had disappeared, and only the bilateral teeth-related primary sensory cortices were active.</p></sec><sec><title>Conclusions</title><p>The present results suggest that adjustments for experimental occlusal interference can be objectively evaluated using fMRI. We expect that this method of evaluating adjustments in occlusal interference, combined with fMRI and the tapping task, could be applied clinically in the future.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Serra, Cm" uniqKey="Serra C">CM Serra</name></author><author><name sortKey="Manns, Ae" uniqKey="Manns A">AE Manns</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Svensson, Kg" uniqKey="Svensson K">KG Svensson</name></author><author><name sortKey="Trulsson, M" uniqKey="Trulsson M">M Trulsson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Svensson, Kg" uniqKey="Svensson K">KG Svensson</name></author><author><name sortKey="Trulsson, M" uniqKey="Trulsson M">M Trulsson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Crespo, Ve" uniqKey="Crespo V">VE Crespo</name></author><author><name sortKey="Crespo, Aa" 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<front><journal-meta><journal-id journal-id-type="nlm-ta">BMC Oral Health</journal-id><journal-id journal-id-type="iso-abbrev">BMC Oral Health</journal-id><journal-title-group><journal-title>BMC Oral Health</journal-title></journal-title-group><issn pub-type="epub">1472-6831</issn><publisher><publisher-name>BioMed Central</publisher-name><publisher-loc>London</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">25304016</article-id><article-id pub-id-type="pmc">4200220</article-id><article-id pub-id-type="publisher-id">454</article-id><article-id pub-id-type="doi">10.1186/1472-6831-14-124</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title>Identification and adjustment of experimental occlusal interference using functional magnetic resonance imaging</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Oda</surname><given-names>Masafumi</given-names></name><address><email>r07oda@fa.kyu-dent.ac.jp</email></address><xref ref-type="aff" rid="Aff1"></xref></contrib><contrib contrib-type="author"><name><surname>Yoshino</surname><given-names>Kenichi</given-names></name><address><email>kyoshino@kyu-dent.ac.jp</email></address><xref ref-type="aff" rid="Aff2"></xref></contrib><contrib contrib-type="author"><name><surname>Tanaka</surname><given-names>Tatsurou</given-names></name><address><email>t-tanaka@kyu-dent.ac.jp</email></address><xref ref-type="aff" rid="Aff1"></xref></contrib><contrib contrib-type="author"><name><surname>Shiiba</surname><given-names>Shunji</given-names></name><address><email>shiiba@kyu-dent.ac.jp</email></address><xref ref-type="aff" rid="Aff3"></xref></contrib><contrib contrib-type="author"><name><surname>Makihara</surname><given-names>Eri</given-names></name><address><email>maki-eri@kyu-dent.ac.jp</email></address><xref ref-type="aff" rid="Aff4"></xref></contrib><contrib contrib-type="author"><name><surname>Miyamoto</surname><given-names>Ikuya</given-names></name><address><email>r08miyamoto@fa.kyu-dent.ac.jp</email></address><xref ref-type="aff" rid="Aff5"></xref></contrib><contrib contrib-type="author"><name><surname>Nogami</surname><given-names>Shinnosuke</given-names></name><address><email>s-nogami@dent.tohoku.ac.jp</email></address><xref ref-type="aff" rid="Aff6"></xref></contrib><contrib contrib-type="author"><name><surname>Kito</surname><given-names>Shinji</given-names></name><address><email>kito@kyu-dent.ac.jp</email></address><xref ref-type="aff" rid="Aff1"></xref></contrib><contrib contrib-type="author"><name><surname>Wakasugi-Sato</surname><given-names>Nao</given-names></name><address><email>n.wakasugi70@gmail.com</email></address><xref ref-type="aff" rid="Aff1"></xref></contrib><contrib contrib-type="author"><name><surname>Matsumoto-Takeda</surname><given-names>Shinobu</given-names></name><address><email>s-takeda@kyu-dent.ac.jp</email></address><xref ref-type="aff" rid="Aff1"></xref></contrib><contrib contrib-type="author"><name><surname>Nishimura</surname><given-names>Shun</given-names></name><address><email>r13nishimura@fa.kyu-dent.ac.jp</email></address><xref ref-type="aff" rid="Aff1"></xref></contrib><contrib contrib-type="author"><name><surname>Murakami</surname><given-names>Keita</given-names></name><address><email>r14murakami@fa.kyu-dent.ac.jp</email></address><xref ref-type="aff" rid="Aff1"></xref></contrib><contrib contrib-type="author"><name><surname>Koga</surname><given-names>Masahiro</given-names></name><address><email>r14koga@fa.kyu-dent.ac.jp</email></address><xref ref-type="aff" rid="Aff1"></xref></contrib><contrib contrib-type="author"><name><surname>Kawagishi</surname><given-names>Shigenori</given-names></name><address><email>kawagisi@kyu-dent.ac.jp</email></address><xref ref-type="aff" rid="Aff7"></xref></contrib><contrib contrib-type="author"><name><surname>Yoshioka</surname><given-names>Izumi</given-names></name><address><email>r13yoshioka@fa.kyu-dent.ac.jp</email></address><xref ref-type="aff" rid="Aff5"></xref></contrib><contrib contrib-type="author"><name><surname>Masumi</surname><given-names>Shin-ichi</given-names></name><address><email>s-masumi@kyu-dent.ac.jp</email></address><xref ref-type="aff" rid="Aff4"></xref></contrib><contrib contrib-type="author"><name><surname>Kimura</surname><given-names>Mitsutaka</given-names></name><address><email>mitu320@nifty.com</email></address><xref ref-type="aff" rid="Aff8"></xref></contrib><contrib contrib-type="author" corresp="yes"><name><surname>Morimoto</surname><given-names>Yasuhiro</given-names></name><address><email>rad-mori@kyu-dent.ac.jp</email></address><xref ref-type="aff" rid="Aff1"></xref><xref ref-type="aff" rid="Aff9"></xref></contrib><aff id="Aff1"><label></label>Division of Oral and Maxillofacial Radiology, Kyushu Dental University, Kitakyushu, Japan</aff><aff id="Aff2"><label></label>Department of Oral Health Management, School of Oral Health Sciences, Kyushu Dental University, Kitakyushu, Japan</aff><aff id="Aff3"><label></label>Division of Dental Anesthesiology, Kyushu Dental University, Kitakyushu, Japan</aff><aff id="Aff4"><label></label>Division of Occlusion and Maxillofacial Reconstruction, Kyushu Dental University, Kitakyushu, Japan</aff><aff id="Aff5"><label></label>Division of Oral Medicine, Kyushu Dental University, Kitakyushu, Japan</aff><aff id="Aff6"><label></label>Division of Oral and Maxillofacial Surgery, Tohoku University Graduate School of Dentistry, Sendai, Japan</aff><aff id="Aff7"><label></label>Division of Multidisciplinary Studies, Kyushu Dental University, Kitakyushu, Japan</aff><aff id="Aff8"><label></label>Kyushu Dental University, Kitakyushu, Japan</aff><aff id="Aff9"><label></label>Center for Oral Biological Research, Kyushu Dental University, Kitakyushu, Japan</aff></contrib-group><pub-date pub-type="epub"><day>10</day><month>10</month><year>2014</year></pub-date><pub-date pub-type="pmc-release"><day>10</day><month>10</month><year>2014</year></pub-date><pub-date pub-type="collection"><year>2014</year></pub-date><volume>14</volume><elocation-id>124</elocation-id><history><date date-type="received"><day>3</day><month>9</month><year>2014</year></date><date date-type="accepted"><day>1</day><month>10</month><year>2014</year></date></history><permissions><copyright-statement>© Oda et al.; licensee BioMed Central Ltd. 2014</copyright-statement><license license-type="open-access"><license-p>This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by/4.0">http://creativecommons.org/licenses/by/4.0</ext-link>), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/publicdomain/zero/1.0/">http://creativecommons.org/publicdomain/zero/1.0/</ext-link>) applies to the data made available in this article, unless otherwise stated.</license-p></license></permissions><abstract id="Abs1"><sec><title>Background</title><p>The purpose of this study was to use functional magnetic resonance imaging (fMRI) to quantify changes in brain activity during experimental occlusal interference.</p></sec><sec><title>Methods</title><p>Fourteen healthy volunteers performed a rhythmical tapping occlusion task with experimental occlusal interference of the right molar tooth at 0 mm (no occlusion), 0.5 mm, and 0.75 mm. The blood-oxygen-level dependent (BOLD) signal was quantified using statistical parametric mapping and compared between rest periods and task periods.</p></sec><sec><title>Results</title><p>In tapping tasks with experimental occlusal interference of 0.75 mm or 0.5 mm, there was clear activation of the contralateral teeth-related primary sensory cortex and Brodmann’s area 46. At 0 and 30 minutes after removal of the experimental occlusal interference, the activation clearly appeared in the bilateral teeth-related primary sensory cortices and Brodmann’s area 46. At 60 minutes after the removal of the experimental occlusal interference, the activation of Brodmann’s area 46 had disappeared, and only the bilateral teeth-related primary sensory cortices were active.</p></sec><sec><title>Conclusions</title><p>The present results suggest that adjustments for experimental occlusal interference can be objectively evaluated using fMRI. We expect that this method of evaluating adjustments in occlusal interference, combined with fMRI and the tapping task, could be applied clinically in the future.</p></sec></abstract><kwd-group xml:lang="en"><title>Keywords</title><kwd>fMRI</kwd><kwd>Occlusion</kwd><kwd>Interference</kwd><kwd>Tooth</kwd><kwd>Brain</kwd><kwd>Function</kwd><kwd>Adjustments</kwd></kwd-group><custom-meta-group><custom-meta><meta-name>issue-copyright-statement</meta-name><meta-value>© The Author(s) 2014</meta-value></custom-meta></custom-meta-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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